Advanced Pathophysiology Knowledge Checks

 

QUESTION 1

  1. A 67-year-old Caucasian woman was brought to the clinic by her son who stated that his mother had become slightly confused over the past several days. She had been stumbling at home and had fallen once but was able to ambulate with some difficulty. She had no other obvious problems and had been eating and drinking. The son became concerned when she forgot her son’s name, so he thought he better bring her to the clinic.  
    PMH-Type II diabetes mellitus (DM) with peripheral neuropathy x 20 years. COPD. Depression after death of spouse several months ago 
    Social/family hx – non contributary except for 30 pack/year history tobacco use.  
    Meds: Metformin 500 mg po BID, ASA 81 mg po qam, escitalopram (Lexapro) 5 mg po q am started 2 months ago 
    Labs-CBC WNL; Chem 7- Glucose-92 mg/dl, BUN 18 mg/dl, Creatinine 1.1 mg/dl, Na+120 mmol/L, 
    K+4.2 mmol/L, CO237 m mol/L, Cl-97 mmol/L.  
    The APRN refers the patient to the ED and called endocrinology for a consult for diagnosis and management of syndrome of inappropriate antidiuretic hormone (SIADH). 

    Question:
    Define SIADH and identify any patient characteristics that may have contributed to the development of SIADH.

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1 points   

QUESTION 2

  1. A 43-year-old female presents to the clinic with a chief complaint of fever, chills, nausea and vomiting and weakness. She has been unable to keep any food, liquids or medications down. The symptoms began 3 days ago and have not responded to ibuprofen, acetaminophen, or Nyquil when she tried to take them. The temperature has reached as high as 102˚F.  

     Allergies: none known to drugs or food or environmental  

     Medications-20 mg prednisone po qd, omeprazole 10 po qam 

     PMH-significant for 20-year history of steroid dependent rheumatoid arthritis (RA). GERD. No other significant illnesses or surgeries. 

    Social-denies alcohol, illicit drugs, vaping, tobacco use 

    Physical exam 

    Thin, ill appearing woman who is sitting in exam room chair as she said she was too weak to climb on the exam table. VS Temp 101.2˚F, BP 98/64, pulse 110, Resp 16, PaO2 96% on room air.  

    ROS negative other than GI symptoms. 

    Based on the patient’s clinical presentation, the APRN diagnoses the patient as having secondary hypocortisolism due to the lack of prednisone the patient was taking for her RA secondary to vomiting.

    Question:

    Explain why the patient exhibited these symptoms? 

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1 points   

QUESTION 3

  1. A 64-year-old Caucasian female presents to the clinic with vague symptoms of non- specific abdominal pain, myalgias, constipation, polyuria, and says she feels “fuzzy headed” much of the time. She had about of kidney stones a few weeks ago and she fortunately was able to pass the small stones without requiring lithotripsy or other interventions. She was told by the urologist to follow up with her primary care provider after the kidney stones has resolved.  
    The APRN examining the patient orders a Chem 7 which revealed a serum Ca++ of 13.1 mg/dl. The APN believes the patient has primary hyperparathyroidism and refers the patient to an endocrinologist who does a complete work up and concurs with the APRN’s diagnosis. 
    Question:
    What is the role of parathyroid hormone in the development of primary hyperparathyroidism? 

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1 points   

QUESTION 4

  1. A 64-year-old Caucasian female presents to the clinic with vague symptoms of non- specific abdominal pain, myalgias, constipation, polyuria, and says she feels “fuzzy headed” much of the time. She had a fracture of her right metatarsal without trauma and currently is wearing a walking boot. She also had a bout of kidney stones a few weeks ago and she fortunately was able to pass the small stones without requiring lithotripsy or other interventions. She was told by the urologist to follow up with her primary care provider after the kidney stones has resolved.  

    The APRN examining the patient orders a Chem 12 which revealed a serum Ca++ of 13.1 mg/dl. The APRN believes the patient has primary hyperparathyroidism and refers the patient to an endocrinologist who does a complete work up and concurs with the APRN’s diagnosis. 

    Question 1 of 2:

    Explain the processes involved in the formation of renal stones in patients with hyperparathyroidism. 

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0.5 points   

QUESTION 5

  1. A 64-year-old Caucasian female presents to the clinic with vague symptoms of non- specific abdominal pain, myalgias, constipation, polyuria, and says she feels “fuzzy headed” much of the time. She had a fracture of her right metatarsal without trauma and currently is wearing a walking boot. She also had a bout of kidney stones a few weeks ago and she fortunately was able to pass the small stones without requiring lithotripsy or other interventions. She was told by the urologist to follow up with her primary care provider after the kidney stones has resolved.  
    The APRN examining the patient orders a Chem 12 which revealed a serum Ca++ of 13.1 mg/dl. The APRN believes the patient has primary hyperparathyroidism and refers the patient to an endocrinologist who does a complete work up and concurs with the APRN’s diagnosis. 
    Question 2 of 2:
    Explain how a patient with hyperparathyroidism is at risk for bone fractures.  

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0.5 points   

QUESTION 6

  1. A 64-year-old Caucasian female who is 4 weeks status post total parathyroidectomy with forearm gland insertion presents to the general surgeon for her post-operative checkup. She states that her mouth feels numb and she feels “tingly all over. The surgeon suspects the patient has hypoparathyroidism secondary to the parathyroidectomy with delayed vascularization of the implanted gland. She orders a Chem 20 to determine what electrolyte abnormalities may be present. The labs reveal a serum Ca++ of 7.1 mg/dl (normal 8.5 mg/dl-10.5 mg/dl) and phosphorous level of 5.6 mg/dl (normal 2.4-4.1 mg/dl).  

    Question:

    What serious consequences of hypoparathyroidism occur and why? — Font family –Andale MonoArialArial BlackBook AntiquaComic Sans MSCourier NewGeorgiaHelveticaImpactSymbolTahomaTerminalTimes New RomanTrebuchet MSVerdanaWebdingsWingdings– Font size –1 (8pt)2 (10pt)3 (12pt)4 (14pt)5 (18pt)6 (24pt)7 (36pt)– Format –HeadingSub Heading 1Sub Heading 2ParagraphFormatted Code– Font family —- Font size —Path: pWords:0

1 points   

QUESTION 7

  1. A 17-year-old boy is brought to the pediatrician’s office by his parents who are concerned about their son’s weight loss despite eating more, frequent urination, unquenchable thirst, and fatigue that is interfering with his school/work activities. He had been seemingly healthy until about 3 months ago when his parents started noticing these symptoms but put these symptoms down to his busy schedule including a part time job. He admits to sleeping more and tires very easily. He denies any other symptoms.  

    PMH-noncontributory. No surgeries or major medical problems. Usual colds and ear infections as a child  

    Allergies-none know  

    Family history- maternal uncle with “some kind of sugar diabetes problem” but parents unclear on the exact disease process 

    Social-denies alcohol, tobacco or illicit drug use. Not sexually active. Junior at local high school and works in a fast food store after school and on weekends. 

    Labs in office: random glucose 220 mg/dl.  

    Based on his symptoms and the glucose level, the pediatrician makes a tentative diagnosis of Diabetes Mellitus type 1 and refers the boy and his parents to an endocrinologist for further work up and management plan.  

    Question 1 of 6:

    The patient exhibited classic signs of Type 1 diabetes. Explain the pathophysiology of “polydipsia.”

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1 points   

QUESTION 8

  1. A 17-year-old boy is brought to the pediatrician’s office by his parents who are concerned about their son’s weight loss despite eating more, frequent urination, unquenchable thirst, and fatigue that is interfering with his school/work activities. He had been seemingly healthy until about 3 months ago when his parents started noticing these symptoms but put these symptoms down to his busy schedule including a part time job. He admits to sleeping more and tires very easily. He denies any other symptoms.  

    PMH-noncontributory. No surgeries or major medical problems. Usual colds and ear infections as a child  

    Allergies-none know  

    Family history- maternal uncle with “some kind of sugar diabetes problem” but parents unclear on the exact disease process 

    Social-denies alcohol, tobacco or illicit drug use. Not sexually active. Junior at local high school and works in a fast food store after school and on weekends. 

    Labs in office: random glucose 220 mg/dl.  

    Based on his symptoms and the glucose level, the pediatrician makes a tentative diagnosis of Diabetes Mellitus type 1 and refers the boy and his parents to an endocrinologist for further work up and management plan.  
    Question 2 of 6:

    The patient exhibited classic signs of Type 1 diabetes. Explain the pathophysiology of “polyuria.”

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1 points   

QUESTION 9

  1. A 17-year-old boy is brought to the pediatrician’s office by his parents who are concerned about their son’s weight loss despite eating more, frequent urination, unquenchable thirst, and fatigue that is interfering with his school/work activities. He had been seemingly healthy until about 3 months ago when his parents started noticing these symptoms but put these symptoms down to his busy schedule including a part time job. He admits to sleeping more and tires very easily. He denies any other symptoms.  
    PMH-noncontributory. No surgeries or major medical problems. Usual colds and ear infections as a child  
    Allergies-none know  
    Family history- maternal uncle with “some kind of sugar diabetes problem” but parents unclear on the exact disease process 
    Social-denies alcohol, tobacco or illicit drug use. Not sexually active. Junior at local high school and works in a fast food store after school and on weekends. 
    Labs in office: random glucose 220 mg/dl.  
    Based on his symptoms and the glucose level, the pediatrician makes a tentative diagnosis of Diabetes Mellitus type 1 and refers the boy and his parents to an endocrinologist for further work up and management plan.  
    Question 3 of 6:
    The patient exhibited classic signs of Type 1 diabetes. Explain the pathophysiology of “polyphagia.”

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1 points   

QUESTION 10

  1. A 17-year-old boy is brought to the pediatrician’s office by his parents who are concerned about their son’s weight loss despite eating more, frequent urination, unquenchable thirst, and fatigue that is interfering with his school/work activities. He had been seemingly healthy until about 3 months ago when his parents started noticing these symptoms but put these symptoms down to his busy schedule including a part time job. He admits to sleeping more and tires very easily. He denies any other symptoms.  

    PMH-noncontributory. No surgeries or major medical problems. Usual colds and ear infections as a child  

    Allergies-none know  

    Family history- maternal uncle with “some kind of sugar diabetes problem” but parents unclear on the exact disease process 

    Social-denies alcohol, tobacco or illicit drug use. Not sexually active. Junior at local high school and works in a fast food store after school and on weekends. 

    Labs in office: random glucose 220 mg/dl.  

    Based on his symptoms and the glucose level, the pediatrician makes a tentative diagnosis of Diabetes Mellitus type 1 and refers the boy and his parents to an endocrinologist for further work up and management plan.  
    Question 4 of 6:
    The patient exhibited classic signs of Type 1 diabetes. Explain the pathophysiology of “weight loss.”

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0.5 points   

QUESTION 11

  1. A 17-year-old boy is brought to the pediatrician’s office by his parents who are concerned about their son’s weight loss despite eating more, frequent urination, unquenchable thirst, and fatigue that is interfering with his school/work activities. He had been seemingly healthy until about 3 months ago when his parents started noticing these symptoms but put these symptoms down to his busy schedule including a part time job. He admits to sleeping more and tires very easily. He denies any other symptoms.  
    PMH-noncontributory. No surgeries or major medical problems. Usual colds and ear infections as a child  
    Allergies-none know  
    Family history- maternal uncle with “some kind of sugar diabetes problem” but parents unclear on the exact disease process 
    Social-denies alcohol, tobacco or illicit drug use. Not sexually active. Junior at local high school and works in a fast food store after school and on weekends. 
    Labs in office: random glucose 220 mg/dl.  
    Based on his symptoms and the glucose level, the pediatrician makes a tentative diagnosis of Diabetes Mellitus type 1 and refers the boy and his parents to an endocrinologist for further work up and management plan.  
    Question 5 of 6:
    The patient exhibited classic signs of Type 1 diabetes. Explain the pathophysiology of “fatigue.”

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0.5 points   

QUESTION 12

  1. A 17-year-old boy is brought to the pediatrician’s office by his parents who are concerned about their son’s weight loss despite eating more, frequent urination, unquenchable thirst, and fatigue that is interfering with his school/work activities. He had been seemingly healthy until about 3 months ago when his parents started noticing these symptoms but put these symptoms down to his busy schedule including a part time job. He admits to sleeping more and tires very easily. He denies any other symptoms.  
    PMH-noncontributory. No surgeries or major medical problems. Usual colds and ear infections as a child  
    Allergies-none know  
    Family history- maternal uncle with “some kind of sugar diabetes problem” but parents unclear on the exact disease process 
    Social-denies alcohol, tobacco or illicit drug use. Not sexually active. Junior at local high school and works in a fast food store after school and on weekends. 
    Labs in office: random glucose 220 mg/dl.  
    Based on his symptoms and the glucose level, the pediatrician makes a tentative diagnosis of Diabetes Mellitus type 1 and refers the boy and his parents to an endocrinologist for further work up and management plan.  
    Question 6 of 6:
    How do genetics and environmental factors contribute to the development of Type 1 diabetes?

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1 points   

QUESTION 13

  1. A 17-year-old boy recently diagnosed with Type I diabetes is brought to the pediatrician’s office by his parents with a chief complaint of “having the flu”. His symptoms began 2 days ago, and he has vomited several times and has not eaten very much. He can’t remember if he took his prescribed insulin for several days because he felt so sick. Random glucose in the office reveals glucose 560 mg/dl and the pediatrician made arrangements for the patient to be admitted to the hospitalist service with an endocrinology consult.  

    BP 124/80mmHg; HR 122bpm; Respirations 32 breaths/min; Temp 97.2˚F; PaO297% on RA 

    Admission labs: Hgb 14.6 g/dl; Hct 58% 

    CMP- Na+ 122mmol/L; K+ 5.3mmol/L; Glucose 560mg/dl; BUN 52mg/dl; Creatinine 4.9mg/dl;  

    Cl- 95mmol/L; Ca++ 8.8mmol/L; AST (SGOT) 248U/L; ALT 198U/L; CK 34/35 IU/L; Cholesterol 198mg/dl;  

    Phosphorus 6.8mg/dl; Acetone Moderate; LDH38U/L; Alkaline Phosphatase 132U/L. 

    Arterial blood gas values were as follows: pH 7.09; Paco220mm Hg; Po2100mm Hg; Sao2 98% (room air) 

    HCO3-7.5mmol/L; anion gap 19.4 

    A diagnosis of diabetic ketoacidosis was made, and the patient was transferred to the Intensive Care Unit (ICU) for close monitoring.  

    Question:

    The hormones involved in intermediary metabolism, exclusive of insulin, that can participate in the development of diabetic ketoacidosis (DKA) are epinephrine, glucagon, cortisol, growth hormone. Describe how they participate in the development of DKA.

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1 points   

QUESTION 14

  1. A 67-year-old African American male presents to the clinic with a chief complaint that he has to “go to the bathroom all the time and I feel really weak.” He states that this has been going on for about 3 days but couldn’t come to the clinic sooner as he went to the Wound Care clinic for a dressing change to his right great toe that has been chronically infected, and he now has osteomyelitis. Patient with known Type II diabetes with poor control. His last HgA1C was 10.2 %. He says he can’t afford the insulin he was prescribed and only takes half of the oral agent he was prescribed. Random glucose in the office revealed glucose of 890 mg/dl. He was immediately referred to the ED by the APRN for evaluation of suspected hyperosmolar hyperglycemic non ketotic syndrome (HHNKS). Also called hyperglycemic hyperosmolar state (HHS).  

    Question:

    Explain the underlying processes that lead to HHNKS or HHS.

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1 points   

QUESTION 15

  1. A 32-year-old woman presented to the clinic complaining of weight gain, swelling in her legs and ankles and a puffy face. She also recently developed hypertension and diabetes type 2. She noted poor short-term memory, irritability, excess hair growth (women), red-ruddy face, extra fat around her neck, fatigue, poor concentration, and menstrual irregularity in addition to muscle weakness. Given her physical appearance and history, a tentative diagnosis of hypercortical function was made. Diagnostics included serum and urinary cortisol and serum adrenocorticotropic hormone (ACTH). MRI revealed a pituitary adenoma.  

    Question:

    How would you differentiate Cushing’s disease from Cushing’s syndrome? 

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1 points   

QUESTION 16

  1. A 47-year-old female is referred to the endocrinologist for evaluation of her chronically elevated blood pressure, hypokalemia, and hypervolemia. The patient’s hypertension has been refractory to the usual medications such as beta blockers, diuretics, and angiotensin-converting enzyme (ACE) inhibitors. After a full work up including serum and urinary electrolyte levels, aldosterone suppression test, plasma aldosterone to renin ratio, and MRI which revealed an autonomous adenoma, the endocrinologist diagnoses the patient with primary hyper-aldosteronism.  

    Question:

    What is the pathogenesis of primary hyper-aldosteronism? 

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1 points   

QUESTION 17

  1. A 47-year-old African American male presents to the clinic with chief complaints of polyuria, polydipsia, polyphagia, and weight loss. He also said that his vison occasionally blurs and that his feet sometimes feel numb.  He has increased hunger despite weight loss and admits to feeling unusually tired. He also complains of “swelling” and enlargement of his abdomen.  

    Past Medical History (PMH) significant for HTN fairly well controlled with and ACE inhibitor; central obesity, and dyslipidemia treated with a statin, Review of systems negative except for chief complaint. Physical exam unremarkable except for decreased filament test both feet. Random glucose in office 290 mg/dl. The APRN diagnoses the patient with type II DM and prescribes oral medication to control the glucose level and also referred the patient to a dietician for dietary teaching. 

    Question:

    What is the basic underlying pathophysiology of Type II DM? 

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1 points   

QUESTION 18

  1. A 21-year-old male was involved in a motorcycle accident and sustained a closed head injury. He is waking up and interacting with his family and medical team. He complained of thirst that doesn’t seem to go away no matter how much water he drinks. The nurses note that he has had 3500 cc of pale-yellow urine in the last 24 hours. Urine was sent for osmolality which was reported as 122 mOsm/L. A diagnosis of probable neurogenic diabetes insipidus was made.  

    Question:

    What causes diabetes insipidus (DI)? 

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0.5 points   

QUESTION 19

  1. A 43-year-old female patient presents to the clinic with complaints of nervousness, racing heartbeat, anxiety, increased perspiration, heat intolerance, hyperactivity and palpitations. She states she had had the symptoms for several months but attributed the symptoms to beginning to care for her elderly mother who has Alzheimer’s Disease. She has lost 15 pounds in the last 3 months without dieting. Her past medical history is significant for rheumatoid arthritis that she has had for the last 10 years well controlled with methotrexate and prednisone. Physical exam is remarkable for periorbital edema, warm silky feeling skin, and palpable thyroid nodules in both lobes of the thyroid. Pending laboratory diagnostics, the APRN diagnoses the patient as having hyperthyroidism, also called Graves’ Disease.

    Question:

    Explain how the negative feedback loop controls thyroid levels.

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1 points   

QUESTION 20

  1. A 43-year-old female patient with known Graves’ Disease presents to the clinic with complaints of nervousnes

Discussion post on how QUALITY CAN INFLUENCE COST.

 Read the following chapters in Financial Management for Nurse Managers and Executives, 5 ed., Jones (2019):

Write 300 words post about how QUALITY CAN INFLUENCE COST. 

APA format with intext citation and references from the chapter using the chapter attached. Feel free to use other sources as long as you give credit to the chapter attached.

Application of Statistics in Health Care

Statistical application and the interpretation of data is important in health care. Review the statistical concepts covered in this topic. In a 750-1,000 word paper, discuss the significance of statistical application in health care. Include the following:

  1. Describe the application of statistics in health care. Specifically discuss its significance to quality, safety, health promotion, and leadership.
  2. Consider your organization or specialty area and how you utilize statistical knowledge. Discuss how you obtain statistical data, how statistical knowledge is used in day-to-day operations and how you apply it or use it in decision making.

Three peer-reviewed, scholarly or professional references are required.

Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion. 

You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.

RUBRIC

psychotherapy with individual

 

Select a client whom you observed or counseled  that suffers from a disorder related to trauma. Then, address the  following in your Practicum Journal:

  • Describe the client (without violating HIPAA regulations) and  identify any pertinent history or medical information, including  prescribed medications.
  • Using the DSM-5, explain and justify your diagnosis for this client.
  • Explain whether any of the therapeutic approaches in this week’s  Learning Resources would be effective with this client. Include expected  outcomes based on these therapeutic approaches. Support your approach  with evidence-based literature.
  • Explain any legal and/or ethical implications related to counseling this client.

This paper is done, I only want the third question answered. My take is Cognitive behavioral therapy for PTSD.

Sociology

 

– Society has changed over the past decade, from style to language and even our environmental resources. Give an example of how social change has effected physical environment, population, innovation, diffusion, and mass media.

– The information revolution was, and still is, an important perspective in social change. In your opinion, how has it changes society and how do you feel it will change society in the future?

– How has modernization changed many underdeveloped nations?

– What are the types of social movements that have occurred in history? When and why did they occur? 

d7 Diabetes in school

Review: “You Tube: Safe at School” by the American Diabetes Association. With your knowledge of who needs to be trained, how would you use this series of 13 chapters to support your students with diabetes? Review Chapter 13 and discuss the legal implications of caring for your students with diabetes. 

Discussion Week 7

Discussion: What Can America Learn From Japan?

As the week’s resources reveal, the Japanese experience demonstrates the importance of cultural issues, such as caring and sharing, that profoundly influence health outcomes. Without considering culture, one cannot begin to explain why Japan is the world’s healthiest nation on most mortality indicators despite having a high proportion of men smoking and the highest rates of low-birth weight babies among rich nations.

Furthermore, health outcomes in Japan are significantly better than those in the U.S., even though the U.S. spends much more on health care. What can the U.S. learn from this country?

Post a brief analysis of how reconstruction after World War II contributed to Japan’s contemporary health status. Then, summarize one significant political feature and one legal feature of Japan’s contemporary health care system that contributes to Japan’s population health status. Offer two reasons (historical, political, legal, and/or cultural) for the disparity between the Japanese and American populations in health achievement. Finally, suggest two lessons other countries can learn from the Japanese experience to improve their own health status. Expand on your insights utilizing the Learning Resources.

Use APA formatting for your Discussion and to cite your resources.

PICOT

1. Need help formulating a PICO question using the information provided in the word document and then I need to briefly explain the model or theory or framework related to your inquiry. 

2. Find an additional reference for the theory or model or framework in a research study and explain its significance to the original PICOT question

Depression Disorders

Write a 5 page research paper about depression disorders. Include:

– Introduction 

– Pathophysiology

– Cure or treatments

– Medications used to treat it 

– Conclusion

– References (At least 5 within the last 5 years)

need help with a term paper

 

Topic: Cultural Assessment

1. Assess and include transcultural beliefs including language, religious practices, socioeconomic status, end-of-life practices, dietary preferences, risky behaviors

2. Identify healthcare behaviors (i.e. nontraditional therapies)

3. Identify challenges and barriers to healthcare and outcomes related to these challenges

4. Develop an evidence-based plan that can be used to improve healthcare outcomes and access to healthcare (including use of IT systems, interdisciplinary members, etc.) for your selected culture. Provide supporting data from peer-reviewed articles.

APA 7th edition formatted, 4-page paper (excluding title and reference pages)

Minimum of 3 references within 5 years